Found: A protein that drives ageing without unleashing inflammation

www.nature.com - 105 poäng - 18 kommentarer - 17736 sekunder sedan

Kommentarer (5)

neom - 13269 sekunder sedan
Paper: https://www.cell.com/immunity/fulltext/S1074-7613(26)00440-1
Granzyme K is the protein.
ethanj8011 - 5505 sekunder sedan
From the abstract of the paper, significantly more nuance.
> Despite persistent immune aging phenotypes, GzmK deficiency markedly attenuated organ aging, effectively uncoupling immune and tissue aging... These findings identify GzmK as a tissue-specific driver of organismal aging but not immune aging or systemic inflammaging.
RobotToaster - 10658 sekunder sedan
Paywall
StilesCrisis - 10958 sekunder sedan
Thank God! Finally, mice that don't age!
agnosticmantis - 14792 sekunder sedan
In mice.